Publications

References

Lee, C.H. indicates my authorship. * Equal first authorship; † corresponding author.

2026

1. Wu, H.*, Lee, C.H.*, Abiri, N., & Ionita-Laza, I. Domain-aware matrix completion for phenotype imputation using electronic health record data with applications in genomic research. Annals of Applied Statistics 20(2), 1010–1032 (2026).

2025

1. Lee, C.H.† Pleiotropy in Multitrait Genome-Wide Association Studies: Approaches and Insights from Schizophrenia–Cognition Analyses. Biological Psychiatry 98(9), 650–651 (2025). [Other peer-reviewed publication]
2. Lee, C.H., Khan, A., Wang, C., Weng, C.H., Buxbaum, J.D., Kiryluk, K., & Ionita-Laza, I. Liability threshold model-based disease risk prediction based on electronic health record phenotypes. Nature Genetics (2025).
3. Luo, Y., Khan, A., Liu, L., Lee, C.H., Perreault, G.J., Pomenti, S.F., Gourh, P., Kiryluk, K., Bernstein, E.J. Cross-Phenotype Genome-Wide Association Study on the Shared Genetic Susceptibility to Systemic Sclerosis and Primary Biliary Cholangitis. Arthritis & Rheumatology 77(6), 727–739 (2025).

2023

1. Jung, S.*, Lee, C.H.*, Sul, J.H., & Han, B. Building an optimal predictive model for imputing tissue-specific gene expression by combining genotype and whole-blood transcriptome data. HGG Adv 4(4), 100223 (2023).

2021

1. Lee, C.H., Shi, H., Pasaniuc, B., Eskin, E., & Han, B. PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics. American Journal of Human Genetics 108(1), 36–48 (2021).

2018

1. Kang, E.Y.*, Lee, C.H.*, Furlotte, N.A., Joo, J.W.J., Kostem, E., Zaitlen, N., Eskin, E., & Han, B. An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Genetics 209(3), 685–698 (2018).
2. Han, B., Akiyama, M., Kim, K.K., Oh, H., Choi, H., Lee, C.H., Jung, S., Lee, H.S., Kim, E.E., Cook, S., Haritunians, T., Yamazaki, K., Park, S.H., Ye, B.D., McGovern, D.P.B., Esaki, M., Kawaguchi, T., Khor, S.S., Taylor, K.D., ... Song, K. Amino acid position 37 of HLA-DRbeta1 affects susceptibility to Crohn's disease in Asians. Human Molecular Genetics 27(22), 3901–3910 (2018).

2017

1. Lee, C.H., Eskin, E., & Han, B. Increasing the power of meta-analysis of genome-wide association studies to detect heterogeneous effects. Bioinformatics 33(14), i379–i388 (2017).
2. Kim, E.E., Lee, S., Lee, C.H., Oh, H., Song, K., & Han, B. FOLD: a method to optimize power in meta-analysis of genetic association studies with overlapping subjects. Bioinformatics 33(24), 3947–3954 (2017).

2016

1. NINDS Stroke Genetics Network (SiGN) & International Stroke Genetics Consortium (ISGC). Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. The Lancet Neurology 15(2), 174–184 (2016). [Consortium contribution]
2. Yang, S.K., Hong, M., Oh, H., Low, H.Q., Jung, S., Ahn, S., Kim, Y., Baek, J., Lee, C.H., Kim, E., Kim, K.M., Ye, B.D., Kim, K.J., Park, S.H., Lee, H.S., Lee, I., Shin, H.D., Han, B., McGovern, D.P.B., ... Song, K. Identification of loci at 1q21 and 16q23 that affect susceptibility to inflammatory bowel disease in Koreans. Gastroenterology 151(6), 1096+ (2016).
3. van 't Hof, F.N., Ruigrok, Y.M., Lee, C.H., Ripke, S., Anderson, G., de Andrade, M., Baas, A.F., Blankensteijn, J.D., Bottinger, E.P., Bown, M.J., Broderick, J., Bijlenga, P., Carrell, D.S., Crawford, D.C., Crosslin, D.R., Ebeling, C., Eriksson, J.G., Fornage, M., Foroud, T., ... de Bakker, P.I. Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms. J Am Heart Assoc 5(7) (2016).
4. Lee, C.H., Cook, S., Lee, J.S., & Han, B. Comparison of Two Meta-Analysis Methods: Inverse-Variance-Weighted Average and Weighted Sum of Z-Scores. Genomics Inform 14(4), 173–180 (2016).
5. Jung, J.*, Lee, C.H.*, Seol, H.S., Choi, Y.S., Kim, E., Lee, E.J., Rhee, J.K., Singh, S.R., Jun, E.S., Han, B., Hong, S.M., Kim, S.C., & Chang, S. Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature. Oncotarget 7(38), 62533–62546 (2016).
6. Han, B., Pouget, J.G., Slowikowski, K., Stahl, E., Lee, C.H., Diogo, D., Hu, X., Park, Y.R., Kim, E., Gregersen, P.K., Dahlqvist, S.R., Worthington, J., Martin, J., Eyre, S., Klareskog, L., Huizinga, T., Chen, W.M., Onengut-Gumuscu, S., Rich, S.S., ... Raychaudhuri, S. A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases. Nat Genet 48(7), 803–810 (2016).

2015

1. Kwak, S.H., Kim, Y.J., Chae, J., Lee, C.H., Han, B., Kim, J.I., Jung, H.S., Cho, Y.M., & Park, K.S. Association of HLA Genotype and Fulminant Type 1 Diabetes in Koreans. Genomics Inform 13(4), 126–131 (2015).